Herbivorous animals that graze on St. John’s wort regularly can receive severe sunburns in addition to being poisoned by the plant. Interesting idea though...to increase effectiveness I presume. 9 Finally, a report suggests that regular use of St. John's wort might also increase the risk of sun-induced cataracts. The medications omeprazole (Prilosec) and lansoprazole (Prevacid) may also increase the tendency of St. John's wort to cause photosensitivity. St. John's wort may pass into breast milk and may cause unwanted effects in a nursing baby. Do not use this product without medical advice … ALSO: This may be an example of assumptive jumping from mammalian lab results to humans. He had had sun reactions before, so it is hard to speculate further. >I am much in support of bioregionalist solutions and actually got my B.S. (I even, being from the Mission district in San Francisco, include in my mailing address-Isley Creek, Shasta Bioregion, USA.) It's my mushroom. Now I haven't asked any albinos doing truckloads of hypericum a day....maybe they'd have a problem. By releasing bugs from afar, they strive to rid our pasture of this scourage from the old country. Restlessness 14. Thank you for the reply. Irritability 12. It is doubtful that medicine will be able to do much more than bandaid repairs as the environment holds more and more complex organics capable of finding THE constitutional weak link in our metabolism. I was born the year WWII began, and spent the first several decades in a world of fewer and less "ripened" eco-toxins and ate food with fewer chemicals and fewer "recombinants". I consider Hypericum to be safe...this is based on personally observing hundreds of people who haved used quality Hypericum preparations (...mine). Photooxidation of lens alpha-crystallin by hypericin. In 1999, alarm spread regarding the association of St. John’s wort with the development of cataracts. Yes, and another really neat thing is that the hypericin (and its phototoxicity in predator insects) is activated, in the presence of oxygen, at the same wavelength that is given off by the Hypericum leaves in the sun. I wanted to start out slow on it, so I only take one pill @ 300 mg. per day. Photochem Photobiol 1999;69: An in vitro test in which a large concentration of hypericin (inconsistent with achievable serum levels), in the absence of any antioxidants normally present in sera, is applied directly on an avascular lens preparation is of questionable clinical significance. Posted by Jay on June 02, 1999 at 08:40:48 My doctor prescribed Paxil for mild depression/anxiety. I don't think many would, but there you go. I am 33 and grew up on the beach and never had this before in my life. Maximum total hypericin plasma concentrations were observed about four hours after drug administration, and were 0, 28, 61, and 159 mcg/mL, respectively. 218-221. The student was using high quantities along with medication and the customer showed little more than passing and perhaps serendipitous symptoms, and I have had GALLONS of my Hypericum tincture and oil go through my grubbies over a couple of decades (usually used by folks going through a stretch of somato-psychic flakiness and often manifesting a peculiar, if temporary, lack of judgement regarding emotions, dosages, and self-monitoring). Hypericin and pseudohypericin: Pharmacokinetics and effects on photosensitivity in humans. Henriette's herbal is one of the oldest and largest herbal medicine sites on the net. Photosensitivity rarely is reported in St. John’s wort clinical trials; however, pale patients who burn easily may not realize they burn more easily. SSI sensitivity was the same in both groups after hypericum treatment. "~ St. Joan’s/John's wort oil protects my skin from radiation damage. Doc Ophthalmol 1994-95;88:339-344. >But of interest to me was the notion that sunlight increased the Wort's anti-viral effects........that sun again......somehow..in some mysterious way linked to this plant and it's effects. From this experience I learned that lesson that we seem to learn over and over again-that the land "lords" will take our very own words, concepts, and ideas and turn them into their own rhetoric. It makes sense, then that phototoxicity was found at the higher, long-term usages (in addition to other factors). He was a student of mine in an 8-month program a few years ago. When used topically, St. John's wort may cause a skin rash. Alternatively, an infusion in olive oil can also be used. New Scientist. The study is created by eHealthMe based on reports of 6 people who take Lamictal and St. john's wort from the FDA, and is updated regularly. Burning or prickling sensation 4. 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